In this issue, we take a careful look at the nature of the Brain-Gut Axis and provide an update on the most recent research and insights emerging from these advances. We review the relationship between BGA and stress, as well as the role of probiotics. We examine probiotics and their general benefits, probiotics for maintenance of health, and probiotics for treating conditions, particularly stress-related conditions. Finally, we look at promising new research on the BGA and its effects on specific conditions and disorders.